Correlation of the variations in prevalence of coronavirus disease 2019 and vitamin D receptor gene polymorphisms in cohorts from 26 countries

Aim: This study aimed to investigate the correlation between rates of coronavirus disease 2019 (COVID-19) prevalence and mortality frequency vitamin D receptor (VDR) gene polymorphisms at loci rs7975232 (ApaI), rs1544410 (BsmI), rs2228570 (FokI), rs731236 (TaqI) in cohorts from 26 countries.Methods: The included use countries where VDR (TaqI), (BsmI) were determined relevant frequencies alleles healthy populations reported: Italy, China, Turkey, Japan, Mexico, Russia, India, Poland, Egypt, Czechia, Ethiopia, Saudi Arabia, Greece, Netherlands, Korea, Spain, United States, Pakistan, Nigeria, Lebanon, Central African Republic, Finland, Iran, Tunisia, Brazil, Croatia. COVID-19 (per million population) reported for each country on 6 December 2020 recorded.Results: A significant positive was found AA genotype (r=0.45, r2=0.20, p=0.02) (r=0.42, r2=0.17, p=0.03) rates. Twenty percent variability 17% could be explained by genotype. Similarly, a TT Seventeen correlations not significant.Conclusion: variation can (ApaI) loci.